stands for Chromatographic Methods – Computer Aided Development.
is a software developed to aid in development and
optimization of HPLC
(High performance liquid chromatography)
analytical methods in either isocratic or gradient modes for
separation of multiple compounds.
enables systematic development and optimization of HPLC methods
with few initial experiments
(starting from 2 runs)
that enable prediction of
the most optimum separation conditions within the full ranges of
the studied method parameters.
Good HPLC methods should provide adequate separation between
compounds of interest in a practical run time.
Development of adequate and robust HPLC methods needs great efforts, experience and time.
This is especially in case of traditional
approach of trial and error in method development.
However,
accelerates the development process by planning
and reducing the trials needed to reach the optimum conditions and
generation of maps.
